Felissa Rose grew up in New York always wanting to perform. At the age of 13, she landed the role of Angela in the cult film Sleepaway Camp (1983). At the age of 17, she applied for early admission to New York University's Tisch School of the Arts and was admitted that fall. Attending The Lee Strasberg institute, she began formal training as a serious actress. Performing in plays around Manhattan put her hard work to the test. Felissa played Denise Savage in Savage in "Limbo," Karen in "Phone Sex," Renée in David Henry Hwang's "M.Butterfly," Willie in "This Property is Condemned," Desdemona in William Shakespeare's "Othello," and many more.
Felissa has since returned to cinema and has appeared in such films as Chris Watson's Zombiegeddon (2003), Andreas Schnaas' Nikos (2003), and Steve Taylor's Sludge (2005). She has also appeared in two films by New Jersey filmmaker Dante Tomaselli: Horror (2002) and Satan's Playground (2005). In addition, Felissa co-hosted the 2005 Village Halloween Parade in New York City with fellow scream queens Debbie Rochon and Raine Brown. She also had a cameo role in the sequel to the original Sleepaway Camp titled Return to Sleepaway Camp. In this sequel, Felissa reprised the role of Angela Baker. The movie had a straight to DVD release on November 4, 2008. She also appears in Hotdog Casserole, written and directed by Chris Raab, as the mother in a dysfunctional family. Felissa starred in a role as Mother in the segment "Dinner Guest" in the anthology horror film, The Perfect House. She also portrayed forensic pathologist Amy Short in the Francis Xavier thriller Poe. In 2016, Felissa starred in the paranormal horror film Family Possessions, written and directed by Tommy Faircloth. The film also starred Mark Patton. In May 2017, she helped produce and acted in the horror film, Death House. Felissa Rose also recently acted in Adam Green’s Victor Crowley.
Recently it was announced that Felissa has joined the cast of Terrifier 2, coming to Netflix in the late summer/early fall of 2020.